細(xì)胞系
| 產(chǎn)品名稱 | 通路概述 | 報(bào)告系統(tǒng)* | 貨號(hào) |
| RLR REPORTER CELLS |
A549 (human) | A549-Dual? KO-MDA5 | NF-κB & IRFs, knockout of human MDA-5 | SEAP / Lucia | a549d-komda5 |
| A549-Dual? KO-RIG-I? | NF-κB & IRFs, knockout of human RIG-I? | SEAP / Lucia | a549d-korigi |
| A549-Dual? KO-MAVS? | NF-κB & IRFs, knockout of human MAVS | SEAP / Lucia | a549d-komavs |
RAW (mouse) | RAW-Lucia? ISG-KO-MDA5 | IRFs, knockout of mouse MDA-5 | Lucia | rawl-komda5 |
| RAW-Lucia? ISG-KO-RIG-I | IRFs, knockout of mouse RIG-I | Lucia | rawl-korigi |
| RAW-Lucia? ISG-KO-MAVS | IRFs, knockout of mouse MAVS | Lucia | Lucia rawl-komavs |
| HEK293 (human) | HEK-Lucia? RIG-I | IRFs, overexpression of human RIG-I | Lucia | hkl-hrigi |
| THP1 (human) | THP1-Dual KO MDA-5 | NF-κB & IRFs, knockout of human MDA-5 | SEAP / Lucia | thpd-komda5 |
| THP1-Dual KO RIG-I | NF-κB & IRFs, knockout of human RIG-I | SEAP / Lucia | thpd-korigi |
| THP1-Dual KO MAVS | NF-κB & IRFs, knockout of human MAVS | SEAP / Lucia | thpd-komavs |
| CYTOSOLIC DNA SENSORS&STING REPORTER CELLS |
B16
(mouse) | B16-Blue?ISG-KO-STING | IRFs， knockout of mouse STING | SEAP | bb-kostg |
HE K 293
(human) | HEK-Blue?ISG-KO-STING | IRFs， knockout of human STING | SEAP | hkb-kostg |
| 293-Dual?hSTING-A162 | Double readout**(IRFs&IFN-B) ， Lucia knocked into IFN-B
S162A human STING transfected | SEAP/Lucia | 293d-a162 |
| 293-Dual?hSTING-H232 | Double readout**(IRFs&IFN-β) ， Lucia knocked into IFN-β,
R71-G230-H232-R293 human STING transfected | SEAP/Lucia | 293d-h232 |
| HEK-Blue STAT6-hSTING R232 | STAT 6-specific SEAP expression | SEAP | hkb-st6r232 |
| 293-Dual?hSTING-R232 | Double readout**(IRFs&IFN-β) ， Lucia knocked into IFN-β，
R71-G 230-R232-R293 human STING transfected | SEAP/Lucia | 293d-r232 |
| 293-Dual?mSTING | Double readout**(IRFs&IFN-β) ， Lucia knocked into IFN-β
mouse STING transfected | SEAP/Lucia | 293d-mstg |
RAW
(mouse) | RAW-Lucia?IS G-KO-cGAS | IRFs， knockout of mouse cGAS | Lucia | rawl-kocgas |
| RAW-Lucia?IS G-KO-IFI16 | IRFs， knockout of mouse IFI16 | Lucia | rawl-koif16 |
| RAW-Lucia?IS G-KO-STING | IRFs， knockout of mouse STING | Lucia | raw-kostg |
| Raw-lucia IS G-KO-TREX1 | IRFs， knockout of mouse TREX1 | Lucia | rawl-kotrex |
THP-1
(human) | THP 1-Dual'KO-cGAS | NF-KB&IRFs， knockout of human cGAS | SEAP/Lucia | thpd-kocgas |
| THP 1-Dual“KO-IFI16 | NF-KB&IRFs， knockout of human IFI16 | SEAP/Lucia | thpd-koifi16 |
| THP 1-Dual'KO-STING | NF-KB&IRFs， knockout of human STING | SEAP/Lucia | thpd-kostg |
| THP 1-Dual'KI-hSTING-A162 | NF-KB&IRFs， knockin of S162A human STING
(DMX A A sensitive isoform | SEAP/Lucia | thpd-a162 |
| THP 1-Dual“KI-hSTING-H232 | NF-KB&IRFs， knockin of R 71-G 230-H 232-R 293 human STING | SEAP/Lucia | thpd-h232 |
| THP 1-Dual'KI hSTING-M155 | NF-KB&IRFs， knockin of V155M human STING
(constitutively active isoform) | SEAP/Lucia | thpd-m155 |
| THP 1-Dual'KI-hSTING-R232 | NF-KB&IRFs， knockin of R 71-G 230-R 232-R 293“wild-type'human STING | SEAP/Lucia | thpd-r232 |
| THP 1-Dual'KI-h STINGS154 | NF-KB&IRFs， knockin of N154S human STING
(constitutively active isoform) | SEAP/Lucia | thpd-s154 |
| THP 1-Dual'KI-m STING | NF-KB&IRFs， knockin of mouse STING | SEAP/Lucia | thpd-mstg |
| THP 1-Dual“KO-TREX1 | NF-KB&IRFs， knockin of human TREX 1 | SEAP/Lucia | thpd-kotrex |
| CYTOSOLIC SENSORS OF INTERMEDIATE METABOLITES OF LPS：ALPK1/TIFA |
| HE K-Blue'KO-ALPK 1 | Knockout(KO) of the ALPK1 gene | SEAP | hkb-koalpk |
| HE K-Blue'KO-TIFA | Knockout(KO) of the TIFA gene | SEAP | hkb-kotifa |
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