克隆號(hào)1A8單克隆抗體與小鼠Ly6G反應(yīng)。Ly6G是GPI錨定的細(xì)胞表面蛋白Ly-6超家族的21-25 kDa成員,在細(xì)胞信號(hào)傳導(dǎo)和細(xì)胞粘附中起作用。Ly6G在發(fā)育過程中由髓系細(xì)胞(包括單核細(xì)胞、巨噬細(xì)胞、粒細(xì)胞和中性粒細(xì)胞)差異表達(dá)。單核細(xì)胞通常在發(fā)育過程中短暫表達(dá)Ly6G,而成熟粒細(xì)胞和外周中性粒細(xì)胞保持表達(dá),這使得Ly6G成為這些群體的良好細(xì)胞表面標(biāo)記。與克隆號(hào)RB6-8C5抗體不同,克隆號(hào)1A8抗體與小鼠Ly6G特異性反應(yīng),沒有與Ly6C交叉反應(yīng)的報(bào)道。
產(chǎn)品詳情
產(chǎn)品貨號(hào) | BE0075-1 |
產(chǎn)品規(guī)格 | 1/5/25/50/100mg |
抗體亞型 | Rat IgG2a,?κ |
推薦同型對(duì)照 | InVivoMAb rat IgG2a isotype control, anti-trinitrophenol(貨號(hào):BE0089) |
推薦抗體稀釋液 | InVivoPure? pH 7.0 Dilution Buffer(貨號(hào):IP0070) |
免疫原 | EL4J cells transfected with Ly6G |
應(yīng)用 | in vivo neutrophil depletion in vivo MDSC depletion Immunofluorescence Immunohistochemistry (paraffin) Immunohistochemistry (frozen) Flow cytometry |
產(chǎn)品形式 | PBS , pH 7.0? Contains no stabilizers or preservatives |
內(nèi)毒素水平 | <2EU/mg (<0.002EU/μg) 使用 LAL gel clotting 測(cè)定 |
純度 | >95% Determined by SDS-PAGE |
無(wú)菌處理 | 0.2 μM filtered |
生產(chǎn)形式 | 從組織培養(yǎng)上清液中純化得到。 |
純化形式 | Protein G |
RRID | AB_1107721 |
分子量大小 | 150 kDa |
保存條件 | 抗體原溶液應(yīng)保存在4°C條件下,不要冷凍保存。 |
?
已發(fā)表參考文獻(xiàn):
in vivo neutrophil depletion | Davis, R. W. t., et al. (2018). “Luminol Chemiluminescence Reports Photodynamic Therapy-Generated Neutrophil Activity In Vivo and Serves as a Biomarker of Therapeutic Efficacy.”?Photochem Photobiol. |
Immunohistochemistry (paraffin) | Coffelt, S. B., et al. (2015). “IL-17-producing gammadelta T cells and neutrophils conspire to promote breast cancer metastasis.”?Nature?522(7556): 345-348. |
Immunohistochemistry (frozen) | Finisguerra, V., et al. (2015). “MET is required for the recruitment of anti-tumoural neutrophils.”?Nature?522(7556): 349-353. |
詳情請(qǐng)咨詢 BioXcell 中國(guó)授權(quán)代理-欣博盛生物科技???
全國(guó)服務(wù)熱線: 4006-800-892? 郵箱: market@neobioscience.com?
深圳: 0755-26755892? ? ? 北京: 010-88594029? ? ? 上海: 021-34613729? ? ? ? ???
廣州:020-87615159? ? ? ? 香港: 852-69410778?
代理品牌網(wǎng)站: m.smblzp.com?
自主品牌網(wǎng)站: www.neobioscience.net