在病毒感染時(shí),細(xì)胞質(zhì)模式識(shí)別受體檢測(cè)病毒核酸并激活銜接蛋白VISA/ MAVS或MITA/STING介導(dǎo)的先天抗病毒反應(yīng)。但是關(guān)于神經(jīng)元內(nèi)分泌功能是否以及如何調(diào)節(jié)先天抗病毒反應(yīng)尚不清楚。最近,武漢大學(xué)的研究團(tuán)隊(duì)在期刊《Cellular & Molecular Immunology》(IF=22.096)上發(fā)表題為“β-adrenoreceptor-triggered PKA activation negatively regulates the innate antiviral response.”的文章,該文章研究表明病毒感染降低了β腎上腺素能激素,腎上腺素和去甲腎上腺素的血清水平,以及它們的受體ADRB1和ADRB2。證明腎上腺素/去甲腎上腺素水平的增加以ADRB1-/2依賴的方式抑制了先天性抗病毒反應(yīng)。機(jī)制上,腎上腺素/去甲腎上腺素刺激激活下游激酶PKA,其催化MITA在S241、S243和T263的磷酸化,抑制MITA激活,并抑制對(duì)DNA病毒的先天免疫反應(yīng)。此外,PKA在T54磷酸化VISA拮抗了對(duì)RNA病毒的先天免疫反應(yīng)。這些發(fā)現(xiàn)揭示了腎上腺素/去甲腎上腺素的先天性抗病毒反應(yīng)的調(diào)節(jié)機(jī)制,并為在緊張和焦慮促進(jìn)的情況下宿主對(duì)病毒感染的易感性增加提供了可能的解釋。
本文中使用了欣博盛Mouse CXCL10 ELISA kit檢測(cè)了血清樣本中這個(gè)細(xì)胞因子的含量。
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1.文章題目:β-adrenoreceptor-triggered PKA activation negatively regulates the innate antiviral response.
期 ???刊:Cellular & Molecular Immunology(影響因子:22.096)
發(fā)表時(shí)間:5?January 2023
作 ???者:Guo Y, Zhang X N, Su S, et al.
作者單位:武漢大學(xué)?
使用產(chǎn)品:Mouse CXCL10 ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36600052/
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2.文章題目:Dopamine‐Integrated Nanointerface between Fibrillar Matrix and Hydrophilic Nanohydroxyapatite Regulates Immune Microenvironment to Boost Endogenous Bone Regeneration.
期 ???刊:Advanced Functional Materials(影響因子:19.924)
發(fā)表時(shí)間:17January 2023
作 ???者:Li X, Li Z, Wang P, et al.
作者單位:四川大學(xué)?
使用產(chǎn)品:Mouse IL-1β, TNF-α, IL-4 and IL-10 ELISA kits
https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202212738
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3.文章題目:Tumor–Antigen Activated Dendritic Cell Membrane-Coated Biomimetic Nanoparticles with Orchestrating Immune Responses Promote Therapeutic Efficacy against Glioma.?
期 ???刊:ACS nano(影響因子:18.027)??
發(fā)表時(shí)間:23?January 2023
作 ???者:Ma X, Kuang L, Yin Y, et al.
作者單位:重慶大學(xué)?
使用產(chǎn)品:Mouse TNF-α ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36688797/
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4.文章題目:Artificial cilia for soft and stable surface covalent immobilization of bone morphogenetic protein-2.
期 ???刊:Bioactive Materials(影響因子:16.874)
發(fā)表時(shí)間:12January 2023
作 ???者:Gan Q, Chen L, Bei H P, et al.
作者單位:香港理工大學(xué)?
使用產(chǎn)品:Human BMP-2 ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36714333/
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5.文章題目:?Inhibition of atherosclerosis progression by modular micelles.
期 ???刊:Journal of Controlled Release(影響因子:11.467)??
發(fā)表時(shí)間:12?January 2023
作 ???者:Wang Q, Duan Y, Jing H, et al.
作者單位:上海交通大學(xué)
使用產(chǎn)品:Mouse TNF-α ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36638843/
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6.文章題目:Dietary genistein increases microbiota-derived short chain fatty acid levels, modulates homeostasis of the aging gut, and extends healthspan and lifespan.
期 ???刊:Pharmacological Research(影響因子:10.334)
發(fā)表時(shí)間:21January 2023
作 ???者:Hou Q, Huang J, Zhao L, et al.
作者單位:中國(guó)農(nóng)業(yè)大學(xué)?
使用產(chǎn)品:Mouse IL-4 ELISA kit
樣本類型:結(jié)腸組織
https://pubmed.ncbi.nlm.nih.gov/36693599/
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7.文章題目:Chemically modified small interfering RNA targeting Hedgehog signaling pathway for rheumatoid arthritis therapy.
期 ???刊:Molecular Therapy-Nucleic Acids(影響因子:10.183)
發(fā)表時(shí)間:1January 2023
作 ???者:Lin L, Zhu S, Huang H, et al.
作者單位:中山大學(xué)附屬第六醫(yī)院?
使用產(chǎn)品:Mouse TNF-α, IL-1β, and IL-6 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36618268/
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8.文章題目:miR-449a exacerbates acute rejection after liver transplantation via targeting PLOD1 in macrophages.
期 ???刊:American Journal of Transplantation(影響因子:9.369)
發(fā)表時(shí)間:12January 2023
作 ???者:Cao Z R, Zheng W X, Jiang Y X, et al.
作者單位:重慶醫(yī)科大學(xué)?
使用產(chǎn)品:Rat IL-1β, IL-6, and TNF-α ELISA kits
https://www.sciencedirect.com/science/article/abs/pii/S1600613522292892
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9.文章題目:Type H vessel/platelet‐derived growth factor receptor β+ perivascular cell disintegration is involved in vascular injury and bone loss in radiation‐induced bone damage.
期 ???刊:Cell Proliferation(影響因子:8.755)
發(fā)表時(shí)間:24January 2023
作 ???者:Li J, Chen X, Ren L, et al.
作者單位:中山大學(xué)口腔醫(yī)院?
使用產(chǎn)品:Mouse PDGF-BB ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36694343/
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10.文章題目:Evaluation the food safety of cultured fat via detection of residues of adipogenic differentiation cocktail in cultured fat with high performance liquid chromatography and enzyme-linked immunosorbent assay.
期 ???刊:Food Research International(影響因子:7.425)
發(fā)表時(shí)間:17January 2023
作 ???者:Song W J, Liu P P, Li C B, et al.
作者單位:南京農(nóng)業(yè)大學(xué)?
使用產(chǎn)品:Porcine Insulin ELISA kit
https://www.sciencedirect.com/science/article/abs/pii/S0963996923000315
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11.文章題目:Salidroside facilitates therapeutic angiogenesis in diabetic hindlimb ischemia by inhibiting ferroptosis.?
期 ???刊:Biomedicine & Pharmacotherapy(影響因子:7.419)?
發(fā)表時(shí)間:12?January 2023?
作 ???者:Wang Y, Han J, Luo L, et al.?
作者單位:重慶大學(xué)
使用產(chǎn)品:Mouse PDGF-BB and VEGF-A ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36638593/
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12.文章題目:An undefined cystatin CsCPI1 from tea plant Camellia sinensis harbors antithrombotic activity.
期 ???刊:Biomedicine & Pharmacotherapy(影響因子:7.419)
發(fā)表時(shí)間:25January 2023
作 ???者:Fang M, Cha J H, Wang H C, et al.
作者單位:廣州醫(yī)科大學(xué)?
使用產(chǎn)品:Rat CXCL1 ELISA kit
樣本類型:腦組織
https://pubmed.ncbi.nlm.nih.gov/36706630/
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13.文章題目:Artemisinin exerts a protective effect in the MPTP mouse model of Parkinson's disease by inhibiting microglial activation via the TLR4/Myd88/NF‐KB pathway.
期 ???刊:CNS Neuroscience & Therapeutics(影響因子:7.035)
發(fā)表時(shí)間:24 January 2023
作 ???者:Lv J, Zhu J, Wang P, et al.
作者單位:錦州醫(yī)科大學(xué)
使用產(chǎn)品:Mouse TNF-α and IL-1β ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36691817/
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14.文章題目:Extracellular Vesicles Expressing CD19 Antigen Improve Expansion and Efficacy of CD19-Targeted CAR-T Cells.
期 ???刊:International Journal of Nanomedicine(影響因子:7.033)
發(fā)表時(shí)間:4?January 2023
作 ???者:Zhang Y, Ge T, Huang M, et al.
作者單位:華中科技大學(xué)
使用產(chǎn)品:Human IFN-γ, TNF-α and IL-2 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36636644/
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15.文章題目:Liujunzi decoction exerts potent antitumor activity in oesophageal squamous cell carcinoma by inhibiting miR-34a/STAT3/IL-6R feedback loop, and modifies antitumor immunity.
期 ???刊:Phytomedicine(影響因子:6.656)
發(fā)表時(shí)間:13January 2023
作 ???者:Han Y, Fan X, Fan L, et al.
作者單位:河南中醫(yī)藥大學(xué)?
使用產(chǎn)品:Human IL-6Rα ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36701994/
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16.文章題目:Evaluation of two laboratory model methods for diarrheal irritable bowel syndrome.
期 ???刊:Molecular Medicine(影響因子:6.376)
發(fā)表時(shí)間:12January 2023
作 ???者:Chen Q, Zhang H, Sun C Y, et al.
作者單位:江西中醫(yī)藥大學(xué)?
使用產(chǎn)品:Rat IgA ELISA kit
樣本類型:結(jié)腸組織
https://pubmed.ncbi.nlm.nih.gov/36635623/
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17.文章題目:Exploring the mechanism by which aqueous Gynura divaricata inhibits diabetic foot based on network pharmacology, molecular docking and experimental verification.
期 ???刊:Molecular Medicine(影響因子:6.376)??
發(fā)表時(shí)間:20?January 2023
作 ???者:Sun Y, Gao C, Liu H, et al.
作者單位:重慶大學(xué)?
使用產(chǎn)品:Rat IL-6 and TNF-α ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36670362/
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18.文章題目:The protective effect of zinc, selenium, and chromium on myocardial fibrosis in the offspring of rats with gestational diabetes mellitus.
期 ???刊:Food & Function(影響因子:6.317)
發(fā)表時(shí)間:20?January 2023
作 ???者:Deng H, Yao X, Cui N, et al.
作者單位:華中科技大學(xué)
使用產(chǎn)品:Rat IL-1β, IL-6?and TNF-α?ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36661107/
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19.文章題目:Aspirin-Loaded Cross-Linked Lipoic Acid Nanodrug Prevents Postoperative Tumor Recurrence by Residual Cancer Cell Killing and Inflammatory Microenvironment Improvement.
期 ???刊:Bioconjugate Chemistry(影響因子:6.069)
發(fā)表時(shí)間:10January 2023
作 ???者:Jing P, Luo Y, Chen Y, et al.
作者單位:四川大學(xué)?
使用產(chǎn)品:Human TNF-α, IL-6, and IL-10 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36626242/
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20.文章題目:Iron oxide nanoparticles cause surface coating-and core chemistry-dependent endothelial cell ferroptosis.
期 ???刊:Nanotoxicology(影響因子:5.881)
發(fā)表時(shí)間:20?January 2023
作 ???者:Zhang X, Kong F, Wang T, et al.
作者單位:中國(guó)醫(yī)學(xué)科學(xué)院基礎(chǔ)醫(yī)學(xué)研究所?
使用產(chǎn)品:Mouse TNF-α ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36660964/
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21.文章題目:Streptococcus suis prophage lysin as a new strategy for combating streptococci-induced mastitis and Streptococcus suis infection.
期 ???刊:Journal of Antimicrobial Chemotherapy(影響因子:5.758)??
發(fā)表時(shí)間:20?January 2023
作 ???者:Li X X, Zhang F Q, Wang S, et al.
作者單位:華中農(nóng)業(yè)大學(xué)?
使用產(chǎn)品:Mouse TNF-α?ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36659862/
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22.文章題目:Hyperoside attenuates Cd-induced kidney injury via inhibiting NLRP3 inflammasome activation and ROS/MAPK/NF-κB signaling pathway in vivo and in vitro.
期 ???刊:Food and Chemical Toxicology(影響因子:5.572)??
發(fā)表時(shí)間:5?January 2023
作 ???者:Li Z, Liao W, Yin X, et al.
作者單位:南方醫(yī)科大學(xué)?
使用產(chǎn)品:Mouse IL-1β, IL-18 and Human IL-1β, IL-6, IL-18 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36610472/
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23.文章題目:Purification, Characterization and Bioactivity of Different Molecular-Weight Fractions of Polysaccharide Extracted from Litchi Pulp.
期 ???刊:Foods(影響因子:5.561)
發(fā)表時(shí)間:1January 2023
作 ???者:Zou X, Cai J, Xiao J, et al.
作者單位:廣東省農(nóng)業(yè)科學(xué)院?
使用產(chǎn)品:Mouse IL-6 and TNF-α ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36613408/
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24.文章題目:E2F1-deficient adipose-derived stem cells improve skin wound closure in mice by upregulating paracrine expression of VEGF and TGF-β1.
期 ???刊:Plastic and Reconstructive Surgery(影響因子:5.169)
發(fā)表時(shí)間:3January 2023
作 ???者:Yi Z, Wu Y, Zhang Q, et al.
作者單位:華中科技大學(xué)?
使用產(chǎn)品:Mouse VEGF and TGF-β1 ELISA kits
https://journals.lww.com/plasreconsurg/Abstract/9900/E2F1__deficient_adipose_derived_stem_cells_improve.1465.aspx
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25.文章題目:Targeting Noncanonical Pyroptosis With a Small Molecular Inhibitor Alleviates Inflammation in the LPS-Induced Keratitis Mouse Model.
期 ???刊:Investigative Ophthalmology & Visual Science(影響因子:4.925)
發(fā)表時(shí)間:3January 2023
作 ???者:Zhang Y, Zhou N, Jiao Y, et al.
作者單位:四川大學(xué)華西醫(yī)院?
使用產(chǎn)品:Human IL-1β ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36595275/
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26.文章題目:The Antiangiogenic and Antitumor Effects of Scoparasin B in Non-Small-Cell Lung Cancer.
期 ???刊:Journal of Natural Products(影響因子:4.803)
發(fā)表時(shí)間:24January 2023
作 ???者:Lin K, Huang L, Zhang Y, et al.
作者單位:廣州醫(yī)科大學(xué)?
使用產(chǎn)品:Human VEGF ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36692021/
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27.文章題目:Canagliflozin Pretreatment Attenuates Myocardial Dysfunction and Improves Postcardiac Arrest Outcomes After Cardiac Arrest and Cardiopulmonary Resuscitation in Mice.
期 ???刊:Cardiovascular Drugs and Therapy(影響因子:3.947)
發(fā)表時(shí)間:7January 2023
作 ???者:Ju F, Abbott G W, Li J, et al.
作者單位:四川大學(xué)華西醫(yī)院?
使用產(chǎn)品:Mouse IL-6 and TNF-α ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36609949/
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28.文章題目:Stanniocalcin-1 secreted by human umbilical mesenchymal stem cells regulates interleukin-10 expression via the PI3K/AKT/mTOR pathway in alveolar macrophages.
期 ???刊:Cytokine(影響因子:3.926)
發(fā)表時(shí)間:3January 2023
作 ???者:Xia T T, Hu R, Shao C J, et al.
作者單位:錦州醫(yī)科大學(xué)?
使用產(chǎn)品:Human IL-10 ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36603482/
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29.文章題目:Yishen Xiezhuo formula ameliorates the development of cisplatin-induced acute kidney injury by attenuating renal tubular epithelial cell senescence.
期 ???刊:Annals of Translational Medicine(影響因子:3.616)
發(fā)表時(shí)間:1January 2023
作 ???者:Zhang Q, Qi J, Luo Q, et al.
作者單位:南方醫(yī)科大學(xué)?
使用產(chǎn)品:Human IL-6 and IL-1β ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36660714/
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30.文章題目:Resveratrol-Loaded Dipalmitoylphosphatidylcholine Liposomal Large Porous Microparticle Inhalations for the Treatment of Bacterial Pneumonia Caused by Acinetobacter baumannii.
期 ???刊:Journal of Aerosol Medicine and Pulmonary Drug Delivery(影響因子:3.44)
發(fā)表時(shí)間:24January 2023
作 ???者:Yu Z, Wu T, Liu X, et al.
作者單位:同濟(jì)大學(xué)醫(yī)學(xué)院?
使用產(chǎn)品:Mouse TNF-α and IL-1β ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36695669/
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31.文章題目:Trilobatin Ameliorates Inflammatory Response by Regulating the miR375-Mediated Fatty Acid Binding Protein 4 Expression in Adipocytes.
期 ???刊:Revista Brasileira de Farmacognosia(影響因子:2.464)
發(fā)表時(shí)間:4January 2023
作 ???者:Li X, Wu Y, Jiang X, et al.
作者單位:重慶理工大學(xué)?
使用產(chǎn)品:Mouse TNF-α and IL-6 ELISA kits
https://link.springer.com/article/10.1007/s43450-022-00356-5
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32.文章題目:Knockdown of TRIM8 alleviates dextran sulfate sodium-induced colitis in mice by inhibiting the NF-κB signaling pathway.?
期 ???刊:Allergologia et Immunopathologia,(影響因子:2.094)??
發(fā)表時(shí)間:1?January 2023
作 ???者:Qiu T, Lv Y, Niu L, et al.
作者單位:陜西省人民醫(yī)院?
使用產(chǎn)品:Mouse IL-1β, IL-6?and TNF-α?ELISA kits
樣本類型:結(jié)腸組織
https://pubmed.ncbi.nlm.nih.gov/36617827/
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33.文章題目:Exposure to particulate matter 2.5 leading to lung microbiome disorder and the alleviation effect of Auricularia auricular-judae polysaccharide.
期 ???刊:International Journal of Occupational Medicine and Environmental Health(影響因子:1.828)
發(fā)表時(shí)間:1January 2023
作 ???者:Zhang Y, He B, Wu L, et al.
作者單位:華北理工大學(xué)?
使用產(chǎn)品:Rat IFN-γ, IL-4, IL-8 and IL-10 ELISA kits
樣本類型:肺組織
https://pubmed.ncbi.nlm.nih.gov/35913271/
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