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Progranulin (human) (rec.) (untagged)
品牌： Adipogen
產(chǎn)品貨號： AG-40A-0188Y-C050
規(guī)格： 50 ug

報價：
折后價：

數(shù)量： - +
產(chǎn)品詳情
* 以下信息僅供參考，詳情請以原廠網(wǎng)站為準(zhǔn)
  • 產(chǎn)品名稱:
    Progranulin (human) (rec.) (untagged)
  • 別名:
    Proepithelin; PEPI; PC Cell-derived Growth Factor
  • 產(chǎn)品描述:
    Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer‘s Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis. EphA2, a member of the large family of Ephrin receptor tyrosine kinases, is also a functional signaling receptor for progranulin as reported recently.
  • 反應(yīng)種屬:
  • 宿主來源:
    HEK 293 cells
  • 實驗應(yīng)用:
  • 靶標(biāo)/特異性:
  • 同種型:
  • 推薦稀釋度:
  • 免疫原:
  • 免疫原種屬:
  • 克隆性:
  • 克隆號:
  • 純化方式:
  • 偶聯(lián):
  • 產(chǎn)品濃度:
    After reconstitution:for 10μg size: 0.1mg/mlfor 50μg size: 1 mg/ml
  • 表達系統(tǒng):
  • 陽性對照:
  • 保存溫度:
    -20°C
  • 運輸溫度:
    BLUE ICE
  • 細(xì)胞定位:
  • 預(yù)期分子量:
    ~74kDa (glycosylated protein by SDS-PAGE)
  • 產(chǎn)品形式:
    solid
  • 存儲溶液:
    Lyophilized. Contains PBS.
  • 有效期:
    Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
  • 產(chǎn)地:
    瑞士
  • 外觀:
  • 生產(chǎn)商:
  • 功能與背景:
  • URL:
  • 靈敏度:
  • 檢測范圍:
  • 檢測方法:
  • 樣本類型:
    Lyophilized. Contains PBS.
  • 產(chǎn)品特點:
  • 純度:
    >98% (SDS-PAGE)
  • 生物活性:
  • 內(nèi)毒素水平:
  • 來源:
  • 表達方式:
  • Accession #:
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  • 分子式:
  • 溶解度:
  • PubChem CID:
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