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Periostin (mouse) ELISA Kit
品牌： Adipogen
產(chǎn)品貨號： AG-45B-0005-KI01
規(guī)格： 96 wells

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數(shù)量： - +
產(chǎn)品詳情
* 以下信息僅供參考，詳情請以原廠網(wǎng)站為準
  • 產(chǎn)品名稱:
    Periostin (mouse) ELISA Kit
  • 別名:
    Osteoblast-specific Factor 2; OSF-2; Postn
  • 產(chǎn)品描述:
    Periostin is a 90-kDa matricellular protein that consists of a typical signal sequence, followed by a cysteine-rich region, an EMI domain (protein-protein interactions), four tandem fasciclin-like domains that are responsible for integrin binding, and a C-terminal region. Periostin was originally isolated as an osteoblast-specific factor that functions as a cell adhesion molecule for pre-osteoblasts and in osteoblast recruitment, attachment and spreading. Periostin is also involved in many fundamental biological processes such as cell proliferation, cell invasion and angiogenesis. Periostin expression is increased by both transforming growth factor beta1 (TGF-beta1) and bone morphogenetic protein 2 (BMP-2). Changes in periostin expression are commonly detected in various cancers and pre-cancerous conditions, and periostin may be involved in regulating cancer cell activities that contribute to tumorigenesis, cancer progression and metastasis. Periostin up-regulation in cancers usually correlates with aggressiveness and/or poor survival. Periostin has shown to be involved in many aspects of allergic inflammation, such as eosinophil recruitment, airway remodeling, development of a Th2 phenotype and increased expression of inflammatory mediators. It is evaluated as a biomarker for bronchial asthma and airway inflammation.
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    +4°C
  • 運輸溫度:
    BLUE ICE
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  • 有效期:
    12 months after the day of manufacturing. See expiry date on ELISA Kit box.
  • 產(chǎn)地:
    瑞士
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