高靈敏、經(jīng)過(guò)充分驗(yàn)證的ELISA試劑盒，3小時(shí)內(nèi)即可得結(jié)果
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血栓素A2（TXA2）參與血小板聚集、血管收縮和生殖功能，但在生理?xiàng)l件下的半衰期僅有37秒。血栓素B2（TXB2）是TXA2非酶水合的穩(wěn)定產(chǎn)物，因此體內(nèi)TXA2的產(chǎn)生通常通過(guò)檢測(cè)TXB2及其代謝物2,3-二酮TXB2來(lái)監(jiān)測(cè)。11-脫氫TXB2是血栓素B2（TXB2）在尿液和血漿中的主要代謝物，由11-OH-脫氫酶的脫氫作用產(chǎn)生。
Enzo Life Sciences提供的TXB2 ELISA試劑盒是一種比色競(jìng)爭(zhēng)法試劑盒，可在3小時(shí)內(nèi)得到結(jié)果，在405 nm處讀取吸光值。在便捷的96孔板式檢測(cè)中，可通過(guò)檢測(cè)TXB2的產(chǎn)生來(lái)評(píng)估COX I的抑制情況。TXB2 ELISA試劑盒提供易于使用的、穩(wěn)定的液體彩色編碼試劑，可幫助減少實(shí)驗(yàn)操作中的錯(cuò)誤。欣博盛生物作為Enzo Life Sciences授權(quán)中國(guó)一級(jí)代理，可提供該產(chǎn)品，歡迎咨詢(xún)。
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產(chǎn)品特點(diǎn)
◆ 高靈敏度，最低可檢測(cè)10.54 pg/ml的TXB2
◆ 高通量，可在3小時(shí)內(nèi)檢測(cè)37份樣本（含復(fù)孔）
◆ 各種樣本類(lèi)型在文獻(xiàn)中被廣泛引用，包括粘膜、組織、血清、血漿、尿液等
◆ 結(jié)果可靠，重復(fù)性好
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產(chǎn)品信息
產(chǎn)品貨號(hào) | ADI-900-002/ ADI-901-002 |
產(chǎn)品名稱(chēng) | TXB2 ELISA kit（血栓素B2 ELISA試劑盒） |
規(guī)格 | 96 wells / 5x96 wells |
靈敏度 | 10.54 pg/ml |
檢測(cè)范圍 | 13.7 - 10,000 pg/ml |
檢測(cè)時(shí)間 | <3 hours |
其他名稱(chēng) | Thromboxane B2 |
應(yīng)用 | ELISA, Colorimetric detection |
樣本類(lèi)型 | For the quantitative determination of TXB2 in culture supernatants, plasma, serum,? saliva, and urine from any species. Cited sample types include cell lysate, coronary? effluent, liver perfusate, platelets, and whole blood. |
檢測(cè)波長(zhǎng) | 405 nm |
適用種屬 | 不限種屬 |
運(yùn)輸溫度 | Blue Ice Not Frozen |
長(zhǎng)期保存溫度 | +4°C |
試劑盒組分 | GxR IgG Microtiter plate, Conjugate, Antibody, Assay buffer, Wash buffer concentrate,? Standard, pNpp Substrate, Stop solution |
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標(biāo)準(zhǔn)曲線(xiàn)示例
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部分產(chǎn)品引用文獻(xiàn)
1.?Chronic edible dosing of Δ9-tetrahydrocannabinol (THC) in nonhuman primates reduces systemic platelet activity and function: S.E. Reitsma, et al.; Am. J. Physiol. Cell Physiol. 322, 370 (2022)
2.?Differential effects of cyclo-oxygenase 1 and 2 inhibition on angiogenesis inhibitor-induced hypertension and kidney damage: K.M. Mirabito Colafella, et al.; Clin. Sci. (Lond.) 136, 675 (2022)
3.?Infection of Galleria mellonella (lepidoptera) larvae with the entomopathogenic fungus Conidiobolus coronatus (entomophthorales) induces apoptosis of hemocytes and affects the concentration of eicosanoids in the hemolymph: A.K. Wronska, et al.; Front. Physiol. 12, 774086 (2022)
4.?Pharmacokinetic and pharmacodynamic profiles of a novel phospholipid-aspirin complex liquid formulation and low dose enteric-coated aspirin: results from a prospective, randomized, crossover study: F. Franchi, et al.; J. Thromb. Thrombolysis 54, 373 (2022)
5.?Antioxidants and/or fish oil reduce intermittent hypoxia-induced inflammation in the neonatal rat terminal ileum: G. Mustafa, et al.; Prostaglandins Other Lipid Mediat. 155, 106565 (2021)
6.?Effects of intestinal flora on the pharmacokinetics and pharmacodynamics of aspirin in high-altitude hypoxia: Y. Sun, et al.; PLoS One 15, e0230197 (2020)
7.?Redundant role of ASK1-mediated p38MAPK activation in human platelet function: K.M. Sledz, et al.; Cell. Signal. 68, 109528 (2020)
8.?Unexpected effects of long-term treatment with acetylsalicylic acid on late phase of pulmonary metastasis in murine model of orthotopic breast cancer: M. Smeda, et al.; PLoS One 15, e0230520 (2020)
9.?A comparative study on the effect of argan oil versus fish oil on risk factors for cardio-vascular disease in high-fat-fed rats: A. Haimeur, et al.; Nutrition 57, 32 (2019)
10.?Critical roles for the phosphatidylinositide 3-kinase isoforms p110β and p110γ in thrombopoietin-mediated priming of platelet function: S.F. Moore, et al.; Sci. Rep. 9, 1468 (2019)
11.?Endothelin-1-Induced Microvascular ROS and Contractility in Angiotensin-II-Infused Mice Depend on COX and TP Receptors: C.S. Wilcox, et al.; Antioxidants (Basel) 8, E193 (2019)
12.?Hyperglycemia enhances constriction of retinal venules via activation of the reverse-mode sodium-calcium exchanger: Y.L. Chen, et al.; Diabetes 68, 1624 (2019)
13.?Ligustrazine inhibits platelet activation via suppression of the Akt pathway: L. Li, et al.; Int. J. Mol. Med. 43, 575 (2019)
14.?Molecular profiling and functional analysis of macrophage-derived tumor extracellular vesicles: C. Cianciaruso, et al.; Cell Rep. 27, 3062 (2019)
15.?Inhibitory Effects of an Orally Active Thromboxane A2 Receptor Antagonist, nstpbp5185, on Atherosclerosis in ApoE-Deficient Mice: S.W. Huang, et al.; Thromb. Haemost. 118, 401 (2018)
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