血清素(5-羥色胺,5-HT)是一種存在于中樞神經(jīng)系統(tǒng)、胃腸道和血液中的單胺,在神經(jīng)傳遞、胃腸運動、止血和心血管完整性方面具有廣泛的生理功能?,F(xiàn)已發(fā)現(xiàn)七個亞類(5-HT 1-7)的5-羥色胺受體,其中大部分是含有七個跨膜結(jié)構(gòu)域的GPCR家族成員,并且是幾種抗抑郁藥物的靶點。5-HT1亞類由五個高度同源的受體組成,通過G(i/o) alpha亞基偶聯(lián)以抑制腺苷酸環(huán)化酶活性。5-HT1A在哺乳動物中的表達在控制情緒的中樞神經(jīng)邊緣通路中最強,包括海馬體、背脊和隔膜的組織。血清素是用于監(jiān)測各種物種的健康狀況或評估行為障礙的關(guān)鍵生物標志物。
ENZO Serotonin ELISA kit是一種比色競爭法酶免疫檢測試劑盒,可在3小時內(nèi)得出結(jié)果。
?
w?高靈敏度,可檢測低至0.293 ng/ml的血清素
w?標準品和樣品不需要酰化
w?已在多種樣本類型中得到驗證
w?高通量,3小時內(nèi)可得到結(jié)果,可檢測多達39個樣本(復(fù)孔)
?
?
產(chǎn)品信息
產(chǎn)品貨號 | ADI-900-175 |
產(chǎn)品名稱 | Serotonin ELISA kit(血清素ELISA試劑盒) |
規(guī)格 | 96 wells |
其他名稱 | 5-HT, 5-hydroxytryptamine |
靈敏度 | 0.293 ng/ml |
檢測范圍 | 0.49 - 500 ng/ml |
檢測時間 | 3 hours |
樣本種屬 | Species independent |
樣本類型 | platelets, plasma, serum, and urine. Cited sample type includes culture supernatant. |
保存溫度 | Store all components at -20°C |
試劑盒組分 | GxR IgG Microtiter plate, Conjugate, Antibody, Assay buffer, Wash buffer concentrate, Standard, pNpp Substrate, Stop solution |
?
部分產(chǎn)品引用文獻
1. Associations of neurotransmitters and the gut microbiome with emotional distress in mixed type of irritable bowel syndrome: Z.A. Barandouzi, et al.; Sci. Rep. 12, 1648 (2022)
2. Enhanced presence of serotonin in nasal cavity after autologous stimulation: F. Salvinelli, et al.; Eur. Rev. Med. Pharmacol. Sci. 256, 2970 (2022)
3. Improvement of several stress response and sleep quality hormones in men and women after sleeping in a bed that protects against electromagnetic fields: E.D.D. Cerro, et al.; Environ. Health 21, 72 (2022)
4, Modulation of Intestinal Corticotropin-Releasing Hormone Signaling by the Herbal Preparation STW 5-II: Possible Mechanisms for Irritable Bowel Syndrome Management: M. Elbadawi, et al.; Pharmaceuticals (Basel) 15, 1121 (2022)
5. Phytochemical screening and effect of Viscum album L. on monoamine oxidase A and B activity and serotonin, dopamine and serotonin receptor 5-HTR1A levels in Galleria mellonealla (Lepidoptera): A. Szurpnicka, et al.; J. Ethnopharmacol. 298, 115604 (2022)
6. Telotristat ethyl reverses myxomatous changes in mice mitral valves: X. Wang, et al.; Front. Cardiovasc. Med. 9, 945672 (2022)
7. Airway basal stem cells generate distinct subpopulations of PNECs: H. Mou, et al.; Cell Rep. 35, 109011 (2021)
8. Analysis of cytokine levels, T regulatory cells and serotonin content in patients with depression: J. Obermanns, et al.; Eur. J. Neurosci. 53, 3476 (2021), Application(s): ELISA using human serum
9. Neuroprotective role of camphor against ciprofloxacin induced depression in rats: modulation of Nrf-2 and TLR4: A. Salama, et al.; Immunopharmacol. Immunotoxicol. 43, 309 (2021)
10. Sensing serotonin secreted from human serotonergic neurons using aptamer-modified nanopipettes: N. Nakatsuka, et al.; Mol. Psychiatry 26, 2753 (2021)
11. Serotonin involvement in okadaic acid-induced diarrhoea in vivo: M.C. Louzao, et al.; Arch. Toxicol. 95, 2797 (2021)
12. Coagulation Profiles of Pulmonary Arterial Hypertension Patients, Assessed by Non-Conventional Hemostatic Tests and Markers of Platelet Activation and Endothelial Dysfunction: E. Vrigkou, et al.; Diagnostics (Basel) 10, 758 (2020)
13. Effects on tactile transmission by serotonin transporter inhibitors at Merkel discs of mouse whisker hair follicles: W. Chang & J.G. Gu; Mol. Pain 16, 1744806920938237 (2020)
14. Perinatal androgens organize sex differences in mast cells and attenuate anaphylaxis severity into adulthood: E. Mackey, et al.; PNAS 117, 23751 (2020), Application(s): Lysed BMMCs (bone marrow-derived Mast Cells) supernatants
15. Platelet inhibition by ticagrelor is protective against diabetic nephropathy in mice: M. Uil, et al.; FASEB J. 34, 13750 (2020), Application(s): Mouse plasma
16. Unexpected effects of long-term treatment with acetylsalicylic acid on late phase of pulmonary metastasis in murine model of orthotopic breast cancer: M. Smeda, et al.; PLoS One 15, e0230520 (2020)
更多詳情請咨詢Enzo Life Sciences授權(quán)全國代理商-欣博盛生物
全國服務(wù)熱線: 4006-800-892? ? ? ? ? ? 郵箱: market@neobioscience.com?
深圳: 0755-26755892? ? ? 北京: 010-88594029? ? ? ?上海: 021-34613729? ? ??
廣州: 020-87615159? ? ? ? 香港: 852-69410778?
代理品牌網(wǎng)站: m.smblzp.com?
自主品牌網(wǎng)站: www.neobioscience.net