促腎上腺皮質(zhì)激素(ACTH)是由腦垂體前葉分泌的多肽激素，作用于腎上腺皮質(zhì)刺激腎上腺類固醇、醛固酮、皮質(zhì)醇和腎上腺雄激素的合成和分泌，也是男子重要的糖皮質(zhì)激素皮質(zhì)醇的主要的調(diào)節(jié)者。ACTH是下丘腦-腦垂體-腎上腺軸的重要組成部分，通常是在生物應(yīng)激反應(yīng)中產(chǎn)生的。當(dāng)血中的皮質(zhì)醇水平增高，腦垂體釋放的促腎上腺皮質(zhì)激素被抑制，相反，腦垂體釋放的促腎上腺皮質(zhì)激素的水平則提高。促腎上腺皮質(zhì)激素在每天清晨(6:00-8:00)達(dá)到峰值，到零時(shí)降到最低狀態(tài)。
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●?靈敏度高，可檢測到低至0.46 pg/ml ACTH含量
●?與類似激素幾乎不反應(yīng)
●?高通量，4.5小時(shí)就可以得到結(jié)果
●?超越半定量Western blot分析的全定量檢測
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Enzo品牌ACTH ELISA kit是一種比色法免疫檢測試劑盒，可在4.5小時(shí)內(nèi)得出檢測結(jié)果。?
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產(chǎn)品信息
產(chǎn)品貨號 | ENZ-KIT138-0001 |
產(chǎn)品名稱 | ACTH ELISA kit（促腎上腺皮質(zhì)激素ELISA試劑盒） |
規(guī)格 | 96 wells |
其他名稱 | Adrenocorticotropic hormone, Corticotropin |
靈敏度 | 0.46 pg/ml |
檢測范圍 | 0.5-165 pg/ml |
檢測時(shí)間 | 4.5 hours |
樣本種屬 | Human |
樣本類型 | plasma |
保存溫度 | +4°C |
試劑盒組分 | Microtiter Plate, Standard, Wash Buffer Concentrate, Buffer, Antibody, Conjugate, Substrate, and Stop Solution |
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部分產(chǎn)品文獻(xiàn)引用
1.Menthol, a bioactive constituent of Mentha, attenuates motion sickness in mice model: Involvement of dopaminergic system: U. M. Deshetty, et al.; J. Food Biochem. (2021)
2.Strain specific stress-modulating effects of candidate probiotics: A systematic screening in a mouse model of chronic restraint stress: L.K. Stenman, et al.; Brain Res. 379, 112376 (2020), Application(s): ELISA using mouse plasma
3.A novel PNPLA6 compound heterozygous mutation identified in a Chinese patient with Boucher-Neuh?user syndrome: R. Zheng, et al.; Mol. Med. Rep. 18, 261 (2018), Application(s): ACTH levels in human serum
4.Liraglutide attenuates the depressive- and anxiety-like behaviour in the corticosterone induced depression model via improving hippocampal neural plasticity: H. Weina, et al.; Behav. Brain Res. 1694, 55 (2018), Application(s): ELISA using mouse plasma
5.β-endorphin regulates alcohol consumption induced by exercise restriction in female mice: C.E. McGonigle, et al.; Alcohol. 53, 51 (2016), Application(s): ACTH levels in mouse plasma
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