Adipogen熱銷產(chǎn)品--Ganglioside GM3 . sodium salt (bovine brain)

2023-02-13

瀏覽次數(shù)： 52

神經(jīng)節(jié)苷脂是酸性鞘糖脂，其在細(xì)胞質(zhì)膜的外部小葉中形成脂筏，特別是在中樞神經(jīng)系統(tǒng)的神經(jīng)元細(xì)胞中。它們參與細(xì)胞增殖、分化、粘附、信號(hào)轉(zhuǎn)導(dǎo)、細(xì)胞間相互作用、腫瘤發(fā)生和轉(zhuǎn)移，神經(jīng)節(jié)苷脂的積累與幾種疾病有關(guān)。神經(jīng)節(jié)苷脂GM3是哺乳動(dòng)物中最豐富的神經(jīng)節(jié)苷脂，它通過(guò)與受體相互作用參與幾種腫瘤過(guò)程，它抑制表皮細(xì)胞生長(zhǎng)并阻斷胰島素受體活性，外源性GM3神經(jīng)節(jié)苷脂抑制動(dòng)脈粥樣硬化。

產(chǎn)品詳情

別名：GM3 . Na; Monosialoganglioside GM3 . Na

來(lái)源：Isolated from bovine brain.

分子式：C59H107N2O21 . Na

分子量：1180.5 . 23.0 (calculated on sphingosine

C18:1 and stearic acid)

CAS號(hào)：54827-14-4

純度：≥98% (TLC)

該產(chǎn)品自上市以來(lái)有多篇文獻(xiàn)引用，品質(zhì)有保證，以下是最新發(fā)表的文獻(xiàn)引用：

1.Exogenous GM3 ganglioside inhibits atherosclerosis via multiple steps: A potential atheroprotective drug: M. Ao, et al.; Pharmacol. Res. 148, 104445 (2019)

2.Ganglioside GM3-Functionalized Reconstituted High-Density Lipoprotein (GM3-rHDL) as a Novel Nanocarrier Enhances Antiatherosclerotic Efficacy of Statins in apoE?/? C57BL/6 Mice: B. Wei, et al.; Pharmaceutics 14, 2534 (2022)

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